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Journal of Pharmaceutical Negative Results ; 13:9880-9884, 2022.
Article in English | EMBASE | ID: covidwho-2232158

ABSTRACT

Background: Among young people, cerebral venous thrombosis (CVT) is a major cause of stroke and females are more likely to develop cerebral venous thrombosis. Objective(s): Thus, the present study aimed to study the clinical profile of CSVT in adults and compare them between both genders and specific age groups. Methodology: The clinical characteristics of 40 male and female patients with and without CVT who had been admitted to the Chettinad Hospital & Research Institute, India, from Feb 2020 to Sep 2021 were included. Result(s): Out of 40 patients, 77.5% were female, and 22.5% were male. The most commonly involved cranial nerve was 7th, contributing 15%, while the involvement of cranial nerves 3rd and 6th contributed 5% and 12.5%, respectively. However, 67.5% of patients had no cranial nerve involved. Covid was diagnosed in 4 patients (10%), and the remaining 36 patients (90%) were diagnosed negative for covid. Cerebrovascular accident (CVA) present in 17 patients. Further, we noticed that 7 patients had left sided stroke and 9 were with right sided stroke. The cranial nerve involved was iii, vi, and vii in 1,3 and 6 patients with CVA, while the cranial nerve involved was iii and vi in 1 and 2 patients without CVA respectively. Further, out of 40 patients, Covid was diagnosed in 2 patients with CVA and 2 without CVA. We have observed a statistically significant difference in focal defects only in with and without CVA patients. Conclusion(s): Males were more likely to develop CVT than females, according to a prior international study. A significant risk factor was alcoholism. The gender gap, clinical profile, and risk variables are not significantly different from earlier Indian investigations. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

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